Advanced Search

Journal Navigation

Journal Home



Contact Us

Table of Contents

Click here to register today!

This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wilhelmi, M.
Right arrow Articles by Haverich, A.
Right arrow Search for Related Content
Social Bookmarking
 Add to CiteULike   Add to Connotea   Add to   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Graft, Vol. 6, No. 1, 6-15 (2003)
DOI: 10.1177/1522162802239751
© 2003 SAGE Publications


Materials Used for Hemodialysis Vascular Access: Current Strategies and a Call to Action

Mathias Wilhelmi, MD

Axel Haverich, MD

Hannover Medical School

Renal replacement programs are an integral therapeutic part of end-stage renal disease. However, the increasing lack of donor organs, associated with an increasing number of patients requiring permanent hemodialysis necessitates the implantation of a hemodialysis access. However, natural vessels are often not or no longer usable after long-standing dialysis. Therefore, arteriovenous grafts, that is, polytetraflouroethylene (PTFE) grafts, are used at increasing frequency. However, PTFE grafts especially are associated with two untoward consequences: high rates of arteriovenous access thrombosis and infection. In this review, current strategies are discussed and requirements for future graft materials are defined. Biological implants show relative resistance to infection and rejection. Therefore, biological implants seem to provide the most useful tool in managing complications associated with hemodialysis vascular access. Thus, it is time to develop new strategies and new graft materials that fulfill the "physiological" requirements of an optimal vascular access to prolong patient survival on dialysis, reducing morbidity and escalating costs.

Key Words: hemodialysis • vascular access • dialysis • shunt • arteriovenous • renal end-stage disease

Add to CiteULike CiteULike   Add to Connotea Connotea   Add to   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?